Katz A M
Hosp Pract. 1978 Jun;13(6):83-91. doi: 10.1080/21548331.1978.11707355.
The rapid loss of myocardial contractility that occurs after coronary occlusion may result from the absence of some critical substrate for cellular metabolism or from accumulation of toxic metabolites. In any event, for a few hours the portion of the myocardium affected by the interruption of blood flow retains its viability. Research into the mechanisms operating during this early period may open the way to reversal of the cellular changes.
冠状动脉闭塞后心肌收缩力迅速丧失，可能是由于缺乏某些细胞代谢关键底物，或有毒代谢产物积累所致。无论如何，在数小时内，受血流中断影响的心肌部分仍保持其活力。对这一早期阶段所涉及机制的研究，可能为逆转细胞变化开辟道路。
