Lundberg J M, Tatemoto K
Eur J Pharmacol. 1982 Sep 10;83(1-2):143-6. doi: 10.1016/0014-2999(82)90300-4.
Local infusions of PYY (3-100 pmol.min-1) caused a slowly developing vasoconstriction of a long duration in the cat submandibular salivary gland. The vasoconstrictor action of PYY was also present after alpha-adrenoceptor blockade and in sympathectomized animals. Local APP infusions caused only weak vasoconstriction. Infusions of PHI and synthetic PHI caused an atropine-resistant submandibular vasodilation. On a molar basis PHI was, however, almost 1000-fold less potent than VIP as vasodilating agent.
在猫的下颌下唾液腺中，局部输注PYY（3 - 100皮摩尔·分钟⁻¹）会引起持续时间较长的缓慢发展的血管收缩。在α-肾上腺素能受体阻断后以及去交感神经的动物中，PYY的血管收缩作用依然存在。局部输注APP仅引起微弱的血管收缩。输注PHI和合成PHI会引起阿托品抵抗性的下颌下血管舒张。然而，按摩尔计算，作为血管舒张剂，PHI的效力比VIP低近1000倍。
