Evill C A, Benness G T
Invest Radiol. 1978 Jul-Aug;13(4):325-7. doi: 10.1097/00004424-197807000-00009.
Preliminary results of comparative studies with a new water-soluble contrast agent are described. The new agent, with the code P.286, is a molecule with 6 iodine atoms attached and only one ionizing group. The sodium salt of the new agent has been compared with sodium iothalamate and metrizamide in dogs. The results suggest that the sodium salt of P.286 is superior in terms of urinary iodine concentration to both sodium iothalamate and metrizamide.
本文描述了一种新型水溶性造影剂的对比研究初步结果。这种代码为P.286的新型造影剂是一种附着有6个碘原子且仅有一个电离基团的分子。已在犬类中将该新型造影剂的钠盐与碘他拉酸钠和甲泛葡胺进行了比较。结果表明,就尿碘浓度而言,P.286的钠盐优于碘他拉酸钠和甲泛葡胺。