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一只犬因肠淋巴管扩张继发蛋白质丢失性肠病。

Protein-losing enteropathy secondary to intestinal lymphangiectasia in a dog.

作者信息

Olson N C, Zimmer J F

出版信息

J Am Vet Med Assoc. 1978 Aug 1;173(3):271-4.

PMID:689969
Abstract

Protein-losing enteropathy secondary to intestinal lymphangiectasia was diagnosed in a 1 1/2 -year-old female Doberman Pinscher. Poor growth rate, intermittent diarrhea, ascites, edema, hypoproteinemia, grossly dilated intestinal lymphatics, and impaired fat absorption characterized the disease. There was histopathologic evidence of dilatation of lacteals and excessive chromium (51Cr)-labeled human albumin in the feces following its intravenous administration. Sixteen weeks of a special diet (high in carbohydrates and medium-chain triglycerides; low in long-chain triglycerides) led to remission of clinical signs. Serum albumin increased over its initial value of 1.09 to 1.7 g/dl, while serum globulin increased from 1.71 to 1.9 g/dl. Following 9 months of dietary therapy, serum albumin increased to 2.1 g/dl and serum globulin increased to 2.6 g/dl.

摘要

一只1岁半的雌性杜宾犬被诊断出患有继发于肠道淋巴管扩张症的蛋白丢失性肠病。生长速率缓慢、间歇性腹泻、腹水、水肿、低蛋白血症、肠道淋巴管明显扩张以及脂肪吸收受损是该疾病的特征。存在组织病理学证据表明乳糜管扩张,并且静脉注射铬(51Cr)标记的人白蛋白后,粪便中有过量的该物质。16周的特殊饮食(高碳水化合物和中链甘油三酯;低长链甘油三酯)使临床症状得到缓解。血清白蛋白从初始值1.09克/分升增加到1.7克/分升,而血清球蛋白从1.71克/分升增加到1.9克/分升。经过9个月的饮食治疗后,血清白蛋白增加到2.1克/分升,血清球蛋白增加到2.6克/分升。

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