Shah P M, Scarton H A, Tsapogas M J
J Anat. 1978 Aug;126(Pt 3):451-8.
Increased haemodynamic forces in the arterial wall may be among the factors responsible for atherogenesis and for determining the severity of the pathological process at a particular site. The present work was designed to help explain apparent asymmetries in the distribution of atheroma at the aorto-iliac bifurcation. A technique was devised for the quantitative evaluation of the geometric anatomy of this region. Measurements were made on 12 female and 14 male cadavers. In all cases there was an asymmetrical left lateral orientation of the abdominal aorta which resulted in a longer right common iliac artery, smaller left common iliac take-off angle and larger left radius of curvature at the aortic-common illiac bifurcation. These differences may explain, through variations in the local haemodynamics, the predilection of the disease for the left iliac artery, particularly in males with their relatively narrow pelvis. Knowledge of both the exact and the average numerical values associated with the local geometry are essential for a detailed haemodynamic study of the effect of these variations on atherogenesis.
动脉壁血流动力学力增加可能是动脉粥样硬化形成的因素之一，也是决定特定部位病理过程严重程度的因素之一。本研究旨在帮助解释主动脉-髂动脉分叉处动脉粥样硬化分布明显不对称的现象。设计了一种技术来定量评估该区域的几何解剖结构。对12具女性尸体和14具男性尸体进行了测量。在所有病例中，腹主动脉均呈不对称的左侧取向，导致右侧髂总动脉较长，左侧髂总动脉起始角度较小，主动脉-髂总动脉分叉处左侧曲率半径较大。这些差异可能通过局部血流动力学的变化来解释疾病对左髂动脉的偏好，特别是在骨盆相对狭窄的男性中。了解与局部几何形状相关的确切数值和平均数值对于详细研究这些变化对动脉粥样硬化形成的血流动力学影响至关重要。
