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兔晶状体纤维的三维结构。扫描电子显微镜再研究。

The three-dimensional organization of lens fibers in the rabbit. A scanning electron microscopic reinvestigation.

作者信息

Willekens B, Vrensen G

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1981;216(4):275-89. doi: 10.1007/BF00455035.

DOI:10.1007/BF00455035
PMID:6910997
Abstract

The importance of the present reinvestigation of the three-dimensional structure of lens fibers in the rabbit is that it has shown the presence of all types of membrane specializations described before in one single lens of one species, the restricted distribution of some specializations, and the conformational changes within one fiber. Interlocking protrusions are present throughout the whole lens and must be considered as the main anchoring processes in the rabbit. Ball-and-socket junctions are present in restricted regions and can be considered an additional anchoring processes. Undulations of the apical and lateral edges of the hexagonal fibers and folds and bends of the lateral surface have a limited distribution. It is postulated that they may play a role in lens changes during accommodation.

摘要

本次对兔晶状体纤维三维结构重新研究的重要性在于,它揭示了在一个物种的单个晶状体中存在之前描述过的所有类型的膜特化结构,某些特化结构的分布受限,以及单个纤维内的构象变化。互锁突起存在于整个晶状体中,在兔眼中必须被视为主要的锚定结构。球窝连接存在于受限区域,可被视为额外的锚定结构。六边形纤维顶端和侧面边缘的波动以及侧面的褶皱和弯曲分布有限。据推测,它们可能在调节过程中晶状体的变化中发挥作用。

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THE ELECTRON MICROSCOPY OF THE NORMAL HUMAN LENS.正常人晶状体的电子显微镜检查
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Freeze-fracture demonstration of intercellular junctions in rabbit lens.兔晶状体细胞间连接的冷冻断裂显示
晶状体硬度和弹性的组织、细胞及分子水平决定因素。
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Preparation and Immunofluorescence Staining of Bundles and Single Fiber Cells from the Cortex and Nucleus of the Eye Lens.从眼晶状体皮质和核中制备束状和单细胞纤维并进行免疫荧光染色。
J Vis Exp. 2023 Jun 9(196). doi: 10.3791/65638.
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EphA2 Affects Development of the Eye Lens Nucleus and the Gradient of Refractive Index.EphA2 影响眼睛晶状体核的发育和折射率梯度。
Invest Ophthalmol Vis Sci. 2022 Jan 3;63(1):2. doi: 10.1167/iovs.63.1.2.
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Age-related changes in eye lens biomechanics, morphology, refractive index and transparency.晶状体生物力学、形态、折射率和透明度的年龄相关变化。
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Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers.鼠晶状体上皮细胞和纤维中的蛋白质组-转录组分析和蛋白质组重塑。
Exp Eye Res. 2019 Feb;179:32-46. doi: 10.1016/j.exer.2018.10.011. Epub 2018 Oct 22.
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Tropomyosin 3.5 protects the F-actin networks required for tissue biomechanical properties.原肌球蛋白 3.5 保护组织生物力学特性所需的 F-肌动蛋白网络。
J Cell Sci. 2018 Nov 29;131(23):jcs222042. doi: 10.1242/jcs.222042.
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The effects of mechanical strain on mouse eye lens capsule and cellular microstructure.机械应变对小鼠眼晶状体囊和细胞微观结构的影响。
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Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells.原肌球蛋白1对肌动蛋白的调节是成熟晶状体纤维细胞之间形成大型桨状突起所必需的。
Invest Ophthalmol Vis Sci. 2016 Aug 1;57(10):4084-99. doi: 10.1167/iovs.16-19949.
Exp Eye Res. 1980 Feb;30(2):211-4. doi: 10.1016/0014-4835(80)90115-3.
4
Lens metabolic cooperation: a study of mouse lens transport and permeability visualized with freeze-substitution autoradiography and electron microscopy.晶状体代谢合作:一项利用冷冻置换放射自显影术和电子显微镜对小鼠晶状体转运和通透性进行可视化的研究。
J Cell Biol. 1980 Aug;86(2):576-89. doi: 10.1083/jcb.86.2.576.
5
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