Chernoiarova O D, Trubitsyna I E
Biull Eksp Biol Med. 1981 Oct;91(10):417-9.
Experiments on rats have demonstrated that changes in the serotonin level in the body intensifies pancreatic function. The pancreas shows the increased contents of trypsinogen and proelastase and those of lysosomal enzymes (cathepsins and acid phosphatase). Administration of serotonin leads to the reduction of the inhibitory properties of blood serum versus proteolytic pancreatic enzymes. Administration of serotonin to animals with the preliminarily ligated pancreatic duct results in the development of pancreatitis with a pronounced fat necrosis of the pancreatic tissue.
对大鼠的实验表明，体内血清素水平的变化会增强胰腺功能。胰腺中胰蛋白酶原、前弹性蛋白酶以及溶酶体酶（组织蛋白酶和酸性磷酸酶）的含量增加。血清素的施用导致血清对胰腺蛋白水解酶的抑制特性降低。对预先结扎胰管的动物施用血清素会导致胰腺炎的发生，并伴有胰腺组织明显的脂肪坏死。
