Schleupner C J, Hamilton J R
Infect Control. 1980 Jan-Feb;1(1):38-42. doi: 10.1017/s0195941700052383.
During a three-week period a pseudoepidemic of fungal infections occurred involving patients from two different services. Trichosporon cutaneum and a Penicillium species were isolated from bronchial washings and sputa obtained after fiberoptic bronchoscopy on eight clinically uninfected patients. Investigation revealed contamination of cocaine solutions used for topical anesthesia during bronchoscopy. Contamination is thought to have occurred during preparation of the solutions by pharmacy personnel. Revision of techniques used in formulating and dispensing the solutions resulted in cessation of the pseudoepidemic.
在三周时间内,发生了一起真菌感染的假性流行,涉及来自两个不同科室的患者。从8名临床未感染患者的纤维支气管镜检查后获得的支气管冲洗液和痰液中分离出了皮状丝孢酵母和一种青霉菌。调查发现,支气管镜检查期间用于局部麻醉的可卡因溶液受到污染。据认为,污染是在药房工作人员配制溶液过程中发生的。对溶液配制和分发所使用技术的修订导致了假性流行的停止。