Genetic polymorphism of glycine-rich beta-glycoprotein in the Italian population.
作者信息
Scherz R, Pflugshaupt R, Bütler R, Peyretti F
出版信息
Hum Hered. 1982;32(1):11-4. doi: 10.1159/000153253.
PMID:6917825
Abstract
Genetic polymorphism of glycine-rich beta-glycoprotein (GBG) was studied in populations from northern and southern Italy, respectively. Gene frequencies were as follows: northern Italy (n = 431): GbS = 0.7675, GbF = 0.2049, GbS 0.7 = 0.0127, GbF1 = 0.0139; southern Italy (n = 161): GbS = 0.7050, GbF = 0.2360, GbS 0.7 = 0.0373, GbF1 = 0.0217. Comparison of these two populations with the Swiss population revealed a significant drift in gene frequencies from north to south. A new GBG phenotype, supposedly heterozygous, with a slow migrating F band and a regular S band in agarose electrophoresis was observed.
摘要
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