Schmidt W, Hendrik H J, Gauwerky J, Junkermann H, Leucht W, Kubli F
Geburtshilfe Frauenheilkd. 1982 Jul;42(7):543-7. doi: 10.1055/s-2008-1036915.
In a prospective study on 125 maternity patients with suspected intra-uterine growth retardation, simple ultrasound biometry (measuring of the distance) and intensive ultra-sound biometry (measurement of the circumference and the surface) were compared. Of 85 newborn born within two weeks following the biometry 34 newborn had intra-uterine growth retardation with a weight percentile smaller than 5, and 32 newborn were growth retarded with a percentile of 5-10. In 19 cases no growth retardation was found. (12 newborn in this group had a weight percentile 10-25). The measurement of the biparietal diameter was capable of diagnosing at the most 50% of the growth retardations (percentile under 5). The accuracy of the diagnosis of intra-uterine growth retardation increased to 85% with the thoraco-abdominal transverse diameter. The so-called borderline cases (percentile 5-10) were diagnosed with the bi-parietal diameter in 38 percent of the cases and by the transverse thoracic diameter in 41% of the cases. Measurement of the circumference of the head resulted in no better measurements than the bi-parietal diameter. The addition of the measurement of the thoracic circumference increased the diagnosis of severe fetal growth retardation (percentile under 5) to 90% and in borderline cases to 88%. The head thorax index and the ratio of head circumference and thoracic circumference increase in our investigation the accuracy of the diagnosis of intra-uterine fetal growth retardation substantially.
在一项针对125例疑似宫内生长受限的孕产妇的前瞻性研究中，对简单超声生物测量法（测量距离）和强化超声生物测量法（测量周长和表面积）进行了比较。在生物测量后两周内出生的85例新生儿中，34例新生儿存在宫内生长受限，体重百分位数小于5，32例新生儿生长受限，百分位数为5-10。19例未发现生长受限。（该组中有12例新生儿体重百分位数为10-25）。双顶径测量最多能诊断出50%的生长受限（百分位数低于5）。采用胸腹部横径时，宫内生长受限的诊断准确率提高到85%。所谓的临界病例（百分位数5-10），双顶径诊断出38%的病例，胸横径诊断出41%的病例。头围测量结果并不比双顶径测量更好。加上胸围测量后，严重胎儿生长受限（百分位数低于5）的诊断率提高到90%，临界病例的诊断率提高到88%。在我们的研究中，头胸指数以及头围与胸围之比大幅提高了宫内胎儿生长受限的诊断准确率。
