Aeilts G D, Sapico F L, Canawati H N, Malik G M, Montgomerie J Z
J Clin Microbiol. 1982 Aug;16(2):218-23. doi: 10.1128/jcm.16.2.218-223.1982.
Methicillin-resistant Staphylococcus aureus (MRSA) colonization and infection in a rehabilitation hospital (Rancho Los Amigos Hospital [RLAH]) were studied from October 1977 to May 1980. Eighty-four episodes of MRSA colonization or infection were observed in 81 patients (attack rate, 0.44 per 100 admissions). The MRSA was considered to have been acquired at RLAH in 65% of the episodes and from transferring hospitals in 34%. The infection rate was 35% among MRSA-colonized patients, and only one death was attributed to MRSA infection. Colonization for more than 100 days occurred most frequently in wounds and anterior nares. All but two of the MRSA isolates were resistant to aminoglycosides, and 80% of those typed belonged to phage type 83A. The patients were allowed to continue participation in rehabilitation programs. Spread of the MRSA occurred in wards where intensive medical and nursing care was being practiced. There was no evidence of MRSA spread in the services with less intense medical and nursing care and where physical and occupational therapy was continued. Patients in a rehabilitation hospital with MRSA colonization may receive intensive physical and occupational therapy as long as special precautions are observed to prevent MRSA spread.
1977年10月至1980年5月，对一家康复医院（兰乔洛斯阿米戈斯医院[RLAH]）耐甲氧西林金黄色葡萄球菌（MRSA）的定植和感染情况进行了研究。在81例患者中观察到84次MRSA定植或感染发作（发病率为每100例入院患者0.44例）。在65%的发作中，MRSA被认为是在RLAH获得的，34%是从转诊医院获得的。MRSA定植患者的感染率为35%，仅有1例死亡归因于MRSA感染。定植超过100天的情况最常发生在伤口和前鼻孔。除两株外，所有MRSA分离株均对氨基糖苷类耐药，80%分型的菌株属于83A噬菌体型。患者被允许继续参加康复项目。MRSA在实施强化医疗和护理的病房中传播。在医疗和护理强度较低且继续进行物理和职业治疗的科室，没有MRSA传播的证据。只要采取特殊预防措施防止MRSA传播，康复医院中MRSA定植的患者可以接受强化物理和职业治疗。
