Pflugradt K, Hartmann N, Voss C
Nahrung. 1978;22(2):219-28. doi: 10.1002/food.19780220213.
The diameter, volume, triglyceride content and number of adipocytes were determined in male Wistar rats at the age of 6 weeks and 2, 3, 12 and 18 months, respectively. A standard diet and water were given ad libitum. The adipocytes were isolated by means of the method of RODBELL. The weight and fat content of the fatty tissues were determined gravimetrically. Age exerts no effect on the adipocyte parameter, nor on the weight and the fat content of the fatty tissue. In contrast to this, there are relationships between adipocyte diameter and the increases in body weight. In all age groups, the increase in size and number of the adipocytes was significantly greater in heavy animals than in light ones. Genetic, hormonal and dietarily-induced factors are discussed as a possible cause. The authors observed no difference in adipocyte size between epididymal and perirenal fatty tissues. As compared to this, the mesenteric adipocytes were smaller.
分别测定了6周龄以及2、3、12和18月龄雄性Wistar大鼠的脂肪细胞直径、体积、甘油三酯含量和数量。给予标准饮食和水，任其自由摄取。采用罗德贝尔法分离脂肪细胞。通过重量法测定脂肪组织的重量和脂肪含量。年龄对脂肪细胞参数以及脂肪组织的重量和脂肪含量均无影响。与此相反，脂肪细胞直径与体重增加之间存在关联。在所有年龄组中，体重较重的动物脂肪细胞大小和数量的增加明显大于体重较轻的动物。讨论了遗传、激素和饮食诱导因素作为可能的原因。作者观察到附睾脂肪组织和肾周脂肪组织之间的脂肪细胞大小没有差异。与此相比，肠系膜脂肪细胞较小。
