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克林霉素与吡利霉素(U-57930E)对金黄色葡萄球菌体外活性的比较。

In vitro comparison of clindamycin and pirlimycin (U-57930E) activity against Staphylococcus aureus.

作者信息

Evans M E, Patterson L S, Stratton C W

出版信息

Antimicrob Agents Chemother. 1982 Aug;22(2):334-5. doi: 10.1128/AAC.22.2.334.

Abstract

The activities of clindamycin and its derivative, pirlimycin (U-57930E), were compared against 100 strains of Staphylococcus aureus, using a microtiter broth dilution technique. Minimal inhibitory concentrations demonstrated that pirlimycin was comparable to clindamycin but offered no increase in activity against either methicillin-susceptible or methicillin-resistant S. aureus.

摘要

采用微量肉汤稀释技术,比较了克林霉素及其衍生物吡利霉素(U - 57930E)对100株金黄色葡萄球菌的抗菌活性。最低抑菌浓度表明,吡利霉素与克林霉素相当,但对甲氧西林敏感或耐药的金黄色葡萄球菌的活性均未增加。

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