Larue-Achagiotis C, Le Magnen J
Neurosci Biobehav Rev. 1980;4 Suppl 1:25-7. doi: 10.1016/0149-7634(80)90043-3.
Six hour food intake following 0 to 6 hours of food deprivation was compared during the light and dark cycle in rats. Changes in the size of the first meal and the length of the first post-meal interval, as a function of deprivation, were related to plasma glucose and free fatty acid levels immediately prior to and 90 minutes following the first meal. It was determined that at night the size of the first meal increased and the relative duration of the post-meal interval decreased as a function of previous fast duration. The shortening of post-meal satiety was associated with the food deprivation induced decrease of blood glucose level and rise of free fatty acids which were observed prior to the meal. The fast induced changes of the meal pattern observed at night and the resulting 6 hour hyperphagia support the conclusion that the duration of post-meal satiety is determined by the meal-to-meal balance between energy intake and utilization.
在大鼠的光照和黑暗周期中，比较了禁食0至6小时后的6小时食物摄入量。作为禁食的函数，第一餐的大小和第一餐后间隔的长度变化与第一餐之前和之后90分钟的血浆葡萄糖和游离脂肪酸水平有关。结果表明，在夜间，第一餐的大小随着先前禁食时间的延长而增加，餐后间隔的相对持续时间则缩短。餐后饱腹感的缩短与禁食引起的血糖水平降低和进食前观察到的游离脂肪酸升高有关。夜间观察到的禁食引起的进食模式变化以及由此产生的6小时摄食过量支持了这样的结论，即餐后饱腹感的持续时间由能量摄入和利用之间的餐间平衡决定。
