47，XYY综合征中的生物胺

Biogenic amines in 47, XYY syndrome.

作者信息

Bioulac B, Benezech M, Renaud B, Roche D, Noël B

出版信息

Neuropsychobiology. 1978;4(6):366-70. doi: 10.1159/000117653.

DOI:10.1159/000117653

Abstract

47, XYYs represent a high percentage of patients admitted in security settings for aggressiveness. By using a polygraphic technique and amine metabolite estimation in the cerebrospinal fluid (CSF), an attempt was made to evaluate the functional activity of the central aminergic system of these patients. No drastic change was observed in sleep patterns of XYYs. The estimation of CSF amine metabolites revealed a normal value for homovanillic acid, but a significant decrease of 5-hydroxyindoleacetic acid turnover.

摘要

47,XYY核型的患者因具有攻击性而在安全机构收治的患者中占比很高。通过使用多导睡眠图技术和测定脑脊液（CSF）中的胺代谢产物，试图评估这些患者中枢胺能系统的功能活性。未观察到47,XYY核型患者的睡眠模式有剧烈变化。脑脊液胺代谢产物的测定显示高香草酸值正常，但5-羟吲哚乙酸周转率显著降低。

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