人类的攻击性与脑脊液胺类代谢产物相关。
Aggression in humans correlates with cerebrospinal fluid amine metabolites.
作者信息
Brown G L, Goodwin F K, Ballenger J C, Goyer P F, Major L F
出版信息
Psychiatry Res. 1979 Oct;1(2):131-9. doi: 10.1016/0165-1781(79)90053-2.
Cerebrospinal fluid of the major central metabolites of serotonin (5HT), norepinephrine (NE), and dopamine (DA)--5-hydroxyindoleacetic acid (5HIAA), 3-methoxy-4-hydroxy=phenylglycol (MHPG), and homovanillic acid (HVA), respectively--were studied in a group of 26 age-similar military men with no history of major psychiatric illness, but with various personality disorders and difficulties adjusting to military life. Independently scored history of aggressive behavior showed a significant negative correlation with 5HIAA (r = -0.78) and a significant positive correlation with MHPG (r = 0.64).
对一组26名年龄相仿、无重大精神疾病史，但患有各种人格障碍且难以适应军事生活的军人，研究了血清素（5HT）、去甲肾上腺素（NE）和多巴胺（DA）的主要中枢代谢产物——分别为5-羟吲哚乙酸（5HIAA）、3-甲氧基-4-羟基苯乙二醇（MHPG）和高香草酸（HVA）的脑脊液。独立评分的攻击行为史与5HIAA呈显著负相关（r = -0.78），与MHPG呈显著正相关（r = 0.64）。
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