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[大鼠咬合功能减退对牙周膜及牙槽骨破骨吸收影响的定量研究]

[Quantitative study of the effect of occlusal hypofunction on periodontal ligament with and alveolar osteoclastic resorption in rats].

作者信息

Levy G, Mailland M L

出版信息

J Biol Buccale. 1980 Mar;8(1):17-31.

PMID:6928848
Abstract

An occlusal hypofunction has been produced by unilateral extraction of the maxillary molars in the rat and its effect has been studied on the antagonistic lower molars during a period of 15 days to 3 months. The quantitative analysis showed that the alveolar width decreased very significantly as early as the fifteen day. This fact was due to a decrease of the periodontal membrane width from the fifteenth day. This decrease was observed until 1 month on the alveolar surface undergoing apposition. The decrease of the alveolar width was also related to a drop of the periodontal membrane width as soon as fifteen days on the surface in resorption. The radicular width remained constant, confirming that it was the bone apposition and not the cementum apposition which caused the narrowing of the periodontal membrane. The quantitative study of the osteoclastic resorption showed that this later decreased but in a non significant on the alveolar surface undergoing remodeling.

摘要

通过单侧拔除大鼠上颌磨牙制造了咬合功能减退,并在15天至3个月的时间段内研究了其对下颌拮抗磨牙的影响。定量分析表明,早在第15天牙槽宽度就非常显著地减小。这一事实是由于从第15天起牙周膜宽度减小所致。在进行附着的牙槽表面,这种减小一直持续到1个月。牙槽宽度的减小也与吸收表面上第15天起牙周膜宽度的下降有关。牙根宽度保持不变,证实是骨附着而非牙骨质附着导致了牙周膜变窄。对破骨细胞吸收的定量研究表明,在进行重塑的牙槽表面,破骨细胞吸收后来减少,但不显著。

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1
[Quantitative study of the effect of occlusal hypofunction on periodontal ligament with and alveolar osteoclastic resorption in rats].[大鼠咬合功能减退对牙周膜及牙槽骨破骨吸收影响的定量研究]
J Biol Buccale. 1980 Mar;8(1):17-31.
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Expression of receptor activator of nuclear factor kappa B ligand relates to inflammatory bone resorption, with or without occlusal trauma, in rats.核因子κB受体活化因子配体的表达与大鼠炎症性骨吸收有关,无论有无咬合创伤。
J Periodontal Res. 2007 Oct;42(5):402-9. doi: 10.1111/j.1600-0765.2007.00960.x.
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Effect of altered occlusal function on transseptal ligament and new bone thicknesses in the periodontium of the rat.改变咬合功能对大鼠牙周膜中跨龈韧带和新骨厚度的影响。
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