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Initial DNA damage and heritable permanent change in pepsinogen isoenzyme pattern in the pyloric mucosae of rats after short-term administration of N-methyl-N'-nitro-N-nitrosoguanidine.

作者信息

Tatematsu M, Saito D, Furihata C, Miyata Y, Nakatsuka T, Ito N, Sugimura T

出版信息

J Natl Cancer Inst. 1980 Apr;64(4):775-81.

PMID:6928991
Abstract
摘要

相似文献

1
Initial DNA damage and heritable permanent change in pepsinogen isoenzyme pattern in the pyloric mucosae of rats after short-term administration of N-methyl-N'-nitro-N-nitrosoguanidine.短期给予N-甲基-N'-硝基-N-亚硝基胍后大鼠幽门黏膜中胃蛋白酶原同工酶模式的初始DNA损伤及可遗传的永久性改变。
J Natl Cancer Inst. 1980 Apr;64(4):775-81.
2
Induction of changes in the pepsinogen content and the pepsinogen isoenzyme pattern of the pyloric mucosa of the rat stomach by short-term administration of stomach carcinogens.短期给予胃致癌物对大鼠胃幽门黏膜胃蛋白酶原含量及胃蛋白酶原同工酶谱的影响
J Natl Cancer Inst. 1981 Nov;67(5):1101-4.
3
Enhancing effects of N-ethyl-N'-nitro-N-nitrosoguanidine and sodium taurocholate on development of pepsinogen 1 decreased pyloric glands in rats initiated with N-methyl-N'-nitro-N-nitrosoguanidine.N-乙基-N'-硝基-N-亚硝基胍和牛磺胆酸钠对用N-甲基-N'-硝基-N-亚硝基胍启动的大鼠胃蛋白酶原1分泌减少的幽门腺发育的增强作用。
Jpn J Cancer Res. 1987 Apr;78(4):312-6.
4
Immunohistochemical demonstration of induction of pyloric glands with low pepsinogen 1 (Pg 1) content in rat stomach by N-methyl-N'-nitro-N-nitrosoguanidine.用N-甲基-N'-硝基-N-亚硝基胍诱导大鼠胃中胃蛋白酶原1（Pg 1）含量低的幽门腺的免疫组织化学证明
Jpn J Cancer Res. 1986 Mar;77(3):238-43.
5
Proliferation kinetics of pepsinogen altered pyloric gland cells in rats treated with N-methyl-N'-nitro-N-nitrosoguanidine.用N-甲基-N'-硝基-N-亚硝基胍处理的大鼠中，胃蛋白酶原改变的幽门腺细胞的增殖动力学。
Carcinogenesis. 1989 May;10(5):907-11. doi: 10.1093/carcin/10.5.907.
6
[Changes in the intracellular localization of pepsinogen-synthesizing polysomes in the gastric mucosa of rats during N-methyl-N'-nitro-N-nitrosoguanidine-induced carcinogenesis].[N-甲基-N'-硝基-N-亚硝基胍诱导大鼠胃癌发生过程中胃黏膜胃蛋白酶原合成多核糖体细胞内定位的变化]
Tsitologiia. 1983 Dec;25(12):1405-10.
7
[Changes in the supramolecular structure of chromatin and pepsinogen synthesis in the gastric mucosa of rats undergoing N-methyl-N'-nitro-N-nitrosoguanidine-induced carcinogenesis].[N-甲基-N'-硝基-N-亚硝基胍诱导致癌的大鼠胃黏膜中染色质超分子结构变化及胃蛋白酶原合成]
Eksp Onkol. 1986;8(1):32-5.
8
[Changes in the content of pepsinogen messenger RNA in the gastric mucosa of rats during N-methyl-N'-nitro-N-nitrosoguanidine-induced carcinogenesis].[N-甲基-N'-硝基-N-亚硝基胍诱导大鼠胃癌发生过程中胃黏膜胃蛋白酶原信使核糖核酸含量的变化]
Eksp Onkol. 1986;8(6):16-8.
9
[Biochemical changes in the glandular part of the rat stomach as affected by N-methyl-N'-nitro-N-nitrosoguanidine].[N-甲基-N'-硝基-N-亚硝基胍对大鼠胃腺部的生化影响]
Vopr Onkol. 1981;27(12):51-6.
10
Proliferation kinetics and development of pepsinogen-altered pyloric gland cells in the glandular stomach of rats treated with chemicals.化学物质处理大鼠腺胃中胃蛋白酶原改变的幽门腺细胞的增殖动力学及发育情况
Prog Clin Biol Res. 1991;369:445-55.

引用本文的文献

1
Human gastric cancer risk screening: From rat pepsinogen studies to the ABC method.人类胃癌风险筛查：从大鼠胃蛋白酶原研究到 ABC 法。
Proc Jpn Acad Ser B Phys Biol Sci. 2021;97(8):462-478. doi: 10.2183/pjab.97.023.
2
Dose-dependent induction of both pepsinogen-altered pyloric glands and adenocarcinomas in the glandular stomach of C3H mice treated with N-methyl-N-nitrosourea.在用N-甲基-N-亚硝基脲处理的C3H小鼠腺胃中，胃蛋白酶原改变的幽门腺和腺癌呈剂量依赖性诱导。
Jpn J Cancer Res. 1997 Mar;88(3):238-44. doi: 10.1111/j.1349-7006.1997.tb00373.x.
3
Organ-specific modification of tumor development by low-dose combinations of agents in a rat wide-spectrum carcinogenesis model.
大鼠广谱致癌模型中低剂量联合用药对肿瘤发生的器官特异性修饰作用
Jpn J Cancer Res. 1991 Jul;82(7):784-92. doi: 10.1111/j.1349-7006.1991.tb02703.x.