Valnes K, Wetterhus S, Ellekjaer E, Halvorsen L, Hovdenak N, Larsen S, Skaug O E, Tønder M, Myren J
Scand J Gastroenterol Suppl. 1980;58:65-70.
Sixty patients with endoscopically confirmed duodenal ulcers were treated with 50 mg of trimipramine daily. After the end of the treatment 45 patients showed healed ulcers. Ulcer healing was not related to serum concentration of trimipramine, but seemed to be influenced by smoking habits and duration of the total and actual disease history.
60例经内镜确诊为十二指肠溃疡的患者,每天接受50毫克三甲丙咪嗪治疗。治疗结束后,45例患者溃疡愈合。溃疡愈合与三甲丙咪嗪的血清浓度无关,但似乎受吸烟习惯以及疾病总病史和实际病史时长的影响。