Siebert G, Amorim A, Kömpf J
Hum Genet. 1980;53(3):421-3. doi: 10.1007/BF00287067.
Linkage data on phosphoglycolate phosphatase (PGP) E.C. 3.1.3.18 and 26 other human genetic markers are presented. One hundred and one families from the southwestern area of Germany were tested. Close linkage between PGP and the following markers could be ruled out: ABO, acP, ADA, GPT, PGM1, GLO, HLA, and PGM3. There is some evidence for possible linkage with MNSs, Rh, Gm and EsD. Family segregation data confirm the hypothesis formerly established by Barker and Hopkinson: three common alleles PG1, PGP2 and PGP3 at an autosomal locus PGP.
本文展示了磷酸乙醇酸磷酸酶(PGP)(E.C. 3.1.3.18)及其他26个人类遗传标记的连锁数据。对来自德国西南部地区的101个家庭进行了检测。可以排除PGP与以下标记之间的紧密连锁:ABO、酸性磷酸酶(acP)、腺苷脱氨酶(ADA)、谷丙转氨酶(GPT)、磷酸葡萄糖变位酶1(PGM1)、β-葡萄糖醛酸酶(GLO)、人类白细胞抗原(HLA)和磷酸葡萄糖变位酶3(PGM3)。有一些证据表明PGP可能与MNSs、Rh、Gm和酯酶D(EsD)存在连锁。家系分离数据证实了巴克和霍普金森之前建立的假设:在常染色体位点PGP上存在三个常见等位基因PG1、PGP2和PGP3。