Huth J F, Holmes E C, Vernon S E, Callery C D, Ramming K P, Morton D L
Am J Surg. 1980 Jul;140(1):9-16. doi: 10.1016/0002-9610(80)90411-0.
Surgical resection plays an important role in the treatment of sarcoma that is metastatic to the lung. Multiple bilateral metastases are not contraindications to surgery. The rapidity of growth and the response to chemotherapy can be accurately determined by the tumor doubling time. Preoperative chemotherapy provides an in vivo measurement of tumor sensitivity, and the response to chemotherapy correlates with prognosis. Since residual microscopic pulmonary disease appears to be responsible for most failures after thoracotomy, attention should be directed toward delivering more effective adjuvant therapy to the lungs.
手术切除在治疗转移至肺部的肉瘤中起着重要作用。多处双侧转移并非手术禁忌证。肿瘤倍增时间可准确确定肿瘤的生长速度和对化疗的反应。术前化疗可在体内测量肿瘤敏感性，且对化疗的反应与预后相关。由于残留的微小肺部病变似乎是开胸术后大多数治疗失败的原因，因此应致力于为肺部提供更有效的辅助治疗。
