Beaglehole R, Prior I A, Foulkes M A, Eyles E F
N Z Med J. 1980 May 28;91(660):375-8.
The pattern of mortality and the influence of blood pressure, serum cholesterol, and body mass on mortality is examined in 1980 adults in four contrasting South Pacific populations. Three of the populations are Polynesian: Pakapuka, an isolated coral atoll, Rarotonga, a less isolated volcanic island, and the New Zealand Maoris, and they are compared with a New Zealand caucasian sample. The baseline examinations were performed in 1963-64 and the cardiovascular risk factors and associated disease were found to be more prevalent in Polynesians with increasing westernisation. The dead or alive status was ascertained in 1974 for 99 percent of the subjects. The age standardised 10-11 year death rates also increased with increasing westernisation from 11.7 percent in Pukapukan men to 26.7 percent in Maori men. The Mantel-Haenszel method of analysis of survivorship data demonstrated a significant inverse relationship between baseline serum cholesterol and mortality in the New Zealand Maoris. Cox's proportional hazards regression model was used to examine the population differences in mortality and it was found that the variables studied do not explain these differences. This study demonstrates the adverse effect of esternisation on the health of Polynesians and suggests that the relationsip between risk factors and mortality differs between populations.
对南太平洋四个不同人群的1980名成年人的死亡率模式以及血压、血清胆固醇和体重对死亡率的影响进行了研究。其中三个人群是波利尼西亚人：孤立的珊瑚环礁帕卡普卡、不太孤立的火山岛拉罗汤加以及新西兰毛利人，将他们与一个新西兰白种人样本进行比较。基线检查于1963 - 1964年进行，发现随着西方化程度的增加，心血管危险因素及相关疾病在波利尼西亚人中更为普遍。1974年确定了99%受试者的生死状况。年龄标准化的10 - 11年死亡率也随着西方化程度的增加而上升，从普卡普卡男性的11.7%上升到毛利男性的26.7%。曼特尔 - 亨塞尔生存数据分析方法表明，新西兰毛利人基线血清胆固醇与死亡率之间存在显著的负相关关系。使用考克斯比例风险回归模型来研究人群死亡率差异，发现所研究的变量并不能解释这些差异。这项研究证明了西方化对波利尼西亚人健康的不利影响，并表明危险因素与死亡率之间的关系在不同人群中有所不同。
