Riber E, Kaaber S
Scand J Dent Res. 1980 Jun;88(3):250-6. doi: 10.1111/j.1600-0722.1980.tb01222.x.
The changes of barrier properties and surface cytology of the palatal mucosa during a denture-wearing period of 12 months has been studied in 18 adult subjects. Transmucosal rates of water transport and that of a 1.10 osmol sucrose solution were registered gravimetrically before denture treatment, after 3 months and after 12 months of denture wearing according to procedures described earlier. The keratinization pattern and the leukocyte migration were evaluated from scrapings taken from the palate and the fitting surface of the denture. The clinical appearance was recorded photographically. After 3 months of denture wearing only minor changes in permeability and surface cytology were observed. After 12 months a distinct grouping of the material was possible with regard to permeability reactions, as seven subjects showed no changes, five subjects demonstrated an increased osmotic activity in the palatal mucosa, and six subjects exhibited a severely decreased barrier function. The color photos revealed inflammatory reactions of the palatal mucosa in the latter group. The cytologic observations showed after 12 months a significant decrease in the proportion of anucleated cells in the inflammatory group, but only minor changes in the remaining material.
对18名成年受试者佩戴义齿12个月期间腭黏膜屏障特性和表面细胞学的变化进行了研究。按照先前描述的程序，在义齿治疗前、佩戴义齿3个月后和12个月后，采用重量法记录水和1.10渗透压蔗糖溶液的经黏膜转运速率。从腭部和义齿贴合面刮取细胞，评估角化模式和白细胞迁移情况。通过摄影记录临床外观。佩戴义齿3个月后，仅观察到渗透性和表面细胞学的轻微变化。12个月后，根据渗透性反应可将材料明显分组，7名受试者无变化，5名受试者腭黏膜的渗透活性增加，6名受试者的屏障功能严重下降。彩色照片显示后一组腭黏膜有炎症反应。细胞学观察显示，12个月后炎症组无核细胞比例显著下降，但其余材料仅有轻微变化。
