White S H
Proc Natl Acad Sci U S A. 1980 Jul;77(7):4048-50. doi: 10.1073/pnas.77.7.4048.
Tanford [Tanford, C. (1979) Proc. Natl. Acad. Sci. USA 76, 3318-3319] used thermodynamic arguments to show that the pressure difference across the bilayer of small phospholipid vesicles must be zero. This paper analyzes the implications of this conclusion in terms of Laplace's law and the basic thermodynamics of interfaces. In its usual form, Laplace's law is of questionable value for the vesicle. If the vesicle is in a state of metastable equilibrium, the surface free energy must be minimal with respect to several thermodynamic variables; the condition (delta F/ delta A) = 0 is not adequate by itself.
坦福德[坦福德，C.（1979年）《美国国家科学院院刊》76，3318 - 3319]运用热力学观点表明，小磷脂囊泡双层膜两侧的压力差必定为零。本文依据拉普拉斯定律和界面基本热力学分析了这一结论的影响。就囊泡而言，拉普拉斯定律的常见形式价值存疑。若囊泡处于亚稳平衡状态，表面自由能相对于几个热力学变量必须最小；仅（δF/δA）= 0这一条件并不充分。
