Sculley P D, Dunley R E
Anesth Prog. 1980 Jan-Feb;27(1):21-3.
A preparation commonly used as a local anesthetic in dentistry has been studied for the presence of antimicrobial activity. The solution, 2% Xylocaine®, with 1:100,000 epinephrine, was shown to inhibit the growth of certain organisms and to be cidal to others. Its cidal activity was significantly less than that of 2% Xylocaine without epinephrine (p < .05). Both solutions demonstrated statistically significant cidal activity when compared to controls (p < .005).
一种常用于牙科局部麻醉的制剂已被研究其抗菌活性。含有1:100,000肾上腺素的2%赛罗卡因溶液被证明能抑制某些微生物的生长,并对其他微生物具有杀菌作用。其杀菌活性明显低于不含肾上腺素的2%赛罗卡因(p < 0.05)。与对照组相比,两种溶液均显示出具有统计学意义的杀菌活性(p < 0.005)。