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1
Antimicrobial activity of a lidocaine preparation.利多卡因制剂的抗菌活性。
Anesth Prog. 1980 Jan-Feb;27(1):21-3.
2
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3
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4
Effects of lidocaine with and without epinephrine on plasma epinephrine and lidocaine concentrations and hemodynamic values during third molar surgery.含肾上腺素和不含肾上腺素的利多卡因对第三磨牙手术期间血浆肾上腺素、利多卡因浓度及血流动力学值的影响。
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5
[Testing the effectiveness of 2% xylocaine with pulp-stimulator].[使用牙髓刺激器测试2%利多卡因的有效性]
Stomatol Vjesn. 1968;2(1-6):553-6.
6
[Low concentration enflurane anesthesia and local administration of epinephrine in rat. Comparison between the lidocaine group and the distilled water group].[低浓度安氟醚麻醉与肾上腺素局部给药在大鼠中的应用。利多卡因组与蒸馏水组的比较]
Ou Daigaku Shigakushi. 1990 Jul;17(2):155-67.
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9
[Determination of the desirable epinephrine concentration containing in dental local anesthetics. Comparison between two lidocaine solutions containing 1/80,000 and 1/200,000 epinephrine].[牙科局部麻醉剂中理想肾上腺素浓度的测定。含1/80,000和1/200,000肾上腺素的两种利多卡因溶液的比较]
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Efficacy of articaine and lidocaine in a primary intraligamentary injection administered with a computer-controlled local anesthetic delivery system.使用计算机控制局部麻醉药输送系统进行初次韧带内注射时阿替卡因和利多卡因的疗效。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Mar;99(3):361-6. doi: 10.1016/j.tripleo.2004.11.009.

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Local anesthetics as a tool for Staphylococcus spp. control: a systematic review.局部麻醉剂作为控制金黄色葡萄球菌的工具:系统评价。
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A review and new insights to antimicrobial action of local anesthetics.局部麻醉药的抗菌作用:综述及新见解。
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3
Antimicrobial effect of topical local anesthetic spray on oral microflora.局部麻醉喷雾剂对口腔微生物群的抗菌作用。
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4
Antimicrobial properties of topical anesthetic liquids containing lidocaine or benzocaine.含利多卡因或苯佐卡因的局部麻醉液的抗菌特性。
Anesth Prog. 1988 Jan-Feb;35(1):9-13.

本文引用的文献

1
Remarks ON GENERAL SPINAL ANALGESIA.关于全身脊髓麻醉的论述
Br Med J. 1909 Nov 13;2(2550):1396-401. doi: 10.1136/bmj.2.2550.1396.
2
The role of the topical anesthetic agent in modifying bacteriologic data obtained by bronchoscopy.
N Engl J Med. 1962 Nov 8;267:957-60. doi: 10.1056/NEJM196211082671903.
3
Bacteriologic studies and effects of anesthetic solutions on bronchial secretions during bronchoscopy.支气管镜检查期间细菌学研究及麻醉溶液对支气管分泌物的影响。
Am Rev Respir Dis. 1961 Sep;84:414-21. doi: 10.1164/arrd.1961.84.3.414.
4
Paraben sensitivity.对羟基苯甲酸酯敏感性
Arch Dermatol. 1966 Jun;93(6):721-3.
5
Effects of topical anesthetics on growth of microorganisms.局部麻醉剂对微生物生长的影响。
Arch Ophthalmol. 1966 Nov;76(5):712-5. doi: 10.1001/archopht.1966.03850010714017.
6
Antimicrobial activity of local anesthetics: lidocaine and procaine.局部麻醉药的抗菌活性:利多卡因和普鲁卡因。
J Infect Dis. 1970 Jun;121(6):597-607. doi: 10.1093/infdis/121.6.597.

利多卡因制剂的抗菌活性。

Antimicrobial activity of a lidocaine preparation.

作者信息

Sculley P D, Dunley R E

出版信息

Anesth Prog. 1980 Jan-Feb;27(1):21-3.

PMID:6933871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2515957/
Abstract

A preparation commonly used as a local anesthetic in dentistry has been studied for the presence of antimicrobial activity. The solution, 2% Xylocaine®, with 1:100,000 epinephrine, was shown to inhibit the growth of certain organisms and to be cidal to others. Its cidal activity was significantly less than that of 2% Xylocaine without epinephrine (p < .05). Both solutions demonstrated statistically significant cidal activity when compared to controls (p < .005).

摘要

一种常用于牙科局部麻醉的制剂已被研究其抗菌活性。含有1:100,000肾上腺素的2%赛罗卡因溶液被证明能抑制某些微生物的生长,并对其他微生物具有杀菌作用。其杀菌活性明显低于不含肾上腺素的2%赛罗卡因(p < 0.05)。与对照组相比,两种溶液均显示出具有统计学意义的杀菌活性(p < 0.005)。