Zamkoff K W, Kirshner J J
Arch Intern Med. 1980 Nov;140(11):1523-4.
A 51-year-man was seen with the diagnosis of acute myelomonocytic leukemia. The WBC count was 380,000/microL at presentation. The serum phosphorus concentration was 0.4 mg/dL and 0.2 mg/dL prior to any phosphorus replacement. Urinary phosphorus excretion was too low to be measured. The patient did not demonstrate any of the usual causes of profound hypophosphatemia with hypophosphaturia. The parathyroid glands were normal at necropsy. Reasons for believing the profound hypophosphatemia was due to phosphorus uptake by the leukemic cells are discussed.
一名51岁男性被诊断为急性粒单核细胞白血病。初诊时白细胞计数为380,000/微升。在未进行任何磷补充之前，血清磷浓度分别为0.4毫克/分升和0.2毫克/分升。尿磷排泄量过低无法测量。该患者未表现出导致严重低磷血症伴低磷尿症的任何常见原因。尸检时甲状旁腺正常。文中讨论了认为严重低磷血症是由于白血病细胞摄取磷所致的原因。
