躁狂症患者的红细胞胆碱浓度升高。
Erythrocyte choline concentrations are elevated in manic patients.
作者信息
Jope R S, Jenden D J, Ehrlich B E, Diamond J M, Gosenfeld L F
出版信息
Proc Natl Acad Sci U S A. 1980 Oct;77(10):6144-6. doi: 10.1073/pnas.77.10.6144.
Abstract
The intracellular choline concentration in erythrocytes of manic patients who never had lithium therapy was 3 times the value for normal human subjects. Lithium therapy increased this value to 11 times normal, and the increase began within the first 2 days of lithium therapy. Plasma choline concentration was normal in untreated manic patients and did not change during lithium therapy.
摘要
从未接受过锂盐治疗的躁狂症患者红细胞内胆碱浓度是正常人类受试者的3倍。锂盐治疗使该值增至正常水平的11倍，且在锂盐治疗的头两天内就开始上升。未经治疗的躁狂症患者血浆胆碱浓度正常，在锂盐治疗期间也未发生变化。
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