Vaillant J M, Morice V, Bertrand J C, Marneur M, Chantalou J P, Dilichen J, Chastang C, Szpirglas H
Rev Stomatol Chir Maxillofac. 1980;81(6):370-5.
A study of the distribution of these cancers demonstrated that they were mainly epidermoid carcinomas (144 cases), cylindromas (38 cases), and sarcomas. The series included 58% of male patients, but the percentage of women is high because of the predominance of muco-epidermoid epitheliomas and hematosarcomas in female patients. Age distribution was identical for both sexes. The period between the first sign and the diagnosis varied according to the histological type (5 months for epidermoid carcinoma, 10 months for the cylindromas, and 28 months for muco-epidermoid epitheliomas). The initial examination revealed the presence of palpable glands in 40% of the cases with epidermoid cancer of the gums, as against 25% of those with facial epidermoid carcinomas. Survival rate after 5 years was 33% for epidermoid cancer, 72% for cylindromas, and 15% for muco-epidermoid epitheliomas. For epidermoid carcinomas, survival was related to their size (56% for T1, 52% for T2, 30% for T3, and 16% for T4). No significant differences in relation to the site of the lesion were found. The incidence of glandular invasion is of the greatest importance. All N3 cases died within 30 months. In fact, two categories of patients can be conveniently distinguished; those with T1, T2, T3, NO who have an overall mean survival rate of 68% after two years, and all the other cases with a mean survival rate of 28%.
对这些癌症分布情况的一项研究表明,它们主要是表皮样癌(144例)、圆柱瘤(38例)和肉瘤。该系列病例中男性患者占58%,但女性患者比例较高,因为黏液表皮样上皮瘤和血液肉瘤在女性患者中占主导地位。男女的年龄分布相同。从出现首个症状到确诊的时间因组织学类型而异(表皮样癌为5个月,圆柱瘤为10个月,黏液表皮样上皮瘤为28个月)。初次检查发现,牙龈表皮样癌患者中有40%可触及淋巴结,而面部表皮样癌患者中这一比例为25%。表皮样癌5年后的生存率为33%,圆柱瘤为72%,黏液表皮样上皮瘤为15%。对于表皮样癌,生存率与其大小有关(T1期为56%,T2期为52%,T3期为30%,T4期为16%)。未发现与病变部位相关的显著差异。淋巴结侵犯的发生率最为重要。所有N3期病例均在30个月内死亡。事实上,可以方便地将患者分为两类;T1、T2、T3、N0期患者两年后的总体平均生存率为68%,而所有其他病例的平均生存率为28%。