Peterson L, Dehner L P, Brunning R D
Am J Clin Pathol. 1981 Feb;75(2):140-8. doi: 10.1093/ajcp/75.2.140.
Acute monoblastic leukemia is an uncommon type of non-lymphocytic leukemia that generally first manifests with signs and symptoms of bone marrow failure. This study describes four patients with acute monoblastic leukemia in whom the initial manifestations of the disorder were related to extramedullary masses. Three of the four patients were children. All patients had bone marrow involvement. The extramedullary mass lesions of acute monoblastic leukemia may be difficult to distinguish from other hematopoietic neoplasms, such as granulocytic sarcoma, malignant lymphoma and malignant histiocytosis, and nonhematopoietic tumors. Examination of the blood and bone marrow, cytochemistry, and electron microscopy are important in identifying the nature of these tumors.
急性单核细胞白血病是一种罕见的非淋巴细胞白血病，通常首先表现为骨髓衰竭的体征和症状。本研究描述了4例急性单核细胞白血病患者，其疾病的初始表现与髓外肿块有关。4例患者中有3例为儿童。所有患者均有骨髓受累。急性单核细胞白血病的髓外肿块病变可能难以与其他造血系统肿瘤（如粒细胞肉瘤、恶性淋巴瘤和恶性组织细胞增多症）以及非造血系统肿瘤相区分。血液和骨髓检查、细胞化学检查及电子显微镜检查对于明确这些肿瘤的性质很重要。
