Miller L P, Steinherz P G, Miller D R
Am J Pediatr Hematol Oncol. 1982 Winter;4(4):425-7. doi: 10.1097/00043426-198224000-00011.
Acute myeloblastic leukemia is suspected usually because of abnormalities of the peripheral blood or bone marrow. In some cases there may also be an extramedullary focus of leukemic cells called a chloroma or granulocytic sarcoma. On occasion, these tumor masses may precede any evidence of leukemia by months or years. They are often misdiagnosed as lymphomas or granulomas. We present here a case of acute myeloblastic leukemia that was preceded by a granulocytic sarcoma of the clavicle. The initial biopsy of the clavicle was thought to be consistent with Ewing's sarcoma. The patient was treated with systemic chemotherapy prior to gross marrow involvement. He has been in continuous complete remission 34 months after the start of chemotherapy and 44 months after the development of granulocytic sarcoma.
急性髓细胞白血病通常是由于外周血或骨髓异常而被怀疑。在某些情况下，也可能存在白血病细胞的髓外病灶，称为绿色瘤或粒细胞肉瘤。有时，这些肿瘤肿块可能在白血病的任何证据出现前数月或数年就已存在。它们常被误诊为淋巴瘤或肉芽肿。我们在此报告一例急性髓细胞白血病，其之前存在锁骨粒细胞肉瘤。锁骨的初始活检被认为与尤因肉瘤相符。在骨髓广泛受累之前，患者接受了全身化疗。自化疗开始34个月以及粒细胞肉瘤出现44个月后，他一直处于持续完全缓解状态。
