Serrano A C
J Clin Psychiatry. 1981 Apr;42(4):154-6.
Haloperidol is safe and effective in children for relieving psychotic symptoms associated with childhood autism, schizophrenia and mental retardation. It is the drug of choice for Tourette's syndrome, and may be useful in nonpsychotic hyperactive or aggressive children to control acute episodes, or when the stimulants normally useful in hyperactive children are ineffective. Such children taking haloperidol not only become calmer, but are often better able to respond to other modalities of therapy and to school instruction. Dosage, initially low, is increased gradually to minimize drowsiness and extrapyramidal symptoms, the most common side effects. Haloperidol in children is usually well-tolerated.
氟哌啶醇对儿童缓解与儿童孤独症、精神分裂症和智力迟钝相关的精神病症状是安全有效的。它是治疗抽动秽语综合征的首选药物,对于非精神病性多动或攻击性儿童,在控制急性发作时可能有用,或者当通常用于治疗多动儿童的兴奋剂无效时也可能有用。服用氟哌啶醇的这类儿童不仅会变得更安静,而且通常更能对其他治疗方式和学校教学做出反应。剂量开始时较低,然后逐渐增加,以尽量减少嗜睡和锥体外系症状,这是最常见的副作用。儿童通常对氟哌啶醇耐受性良好。