维生素B12的生物合成：在咕啉环系统形成过程中产生的挥发性片段的性质。
Biosynthesis of vitamin B12: nature of the volatile fragment generated during formation of the corrin ring system.
作者信息
Mombelli L, Nussbaumer C, Weber H, Müller G, Arigoni D
出版信息
Proc Natl Acad Sci U S A. 1981 Jan;78(1):11-2. doi: 10.1073/pnas.78.1.11.
Abstract
It is shown with the help of radiolabeled substrates that biological formation of the corrin ligand system of cobyrinic acid is linked with the release of an equivalent of acetic acid from a hydroporphinoid precursor in which the C-20 atom has undergone methylation prior to its excision from the macrocycle.
摘要
通过放射性标记底物表明，钴胺酸的咕啉配体系统的生物合成与从类卟啉前体释放等量乙酸有关，在该前体中，C-20原子在从大环上切除之前已经发生甲基化。
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本文引用的文献
1
Ring contraction of hydroporphinoid to corrinoid complexes.氢卟啉环收缩为钴胺素类复合物。
Proc Natl Acad Sci U S A. 1981 Jan;78(1):16-9. doi: 10.1073/pnas.78.1.16.
2
Biosynthesis of vitamin B12: mode of incorporation of factor III into cobyrinic acid.维生素B12的生物合成：因子III掺入钴胺酸的方式。
Proc Natl Acad Sci U S A. 1981 Jan;78(1):9-10. doi: 10.1073/pnas.78.1.9.
3
Biosynthesis of vitamin B12: identity of fragment extruded during ring contraction to the corrin macrocycle.维生素B12的生物合成：在向咕啉大环收缩过程中挤出片段的鉴定。
Proc Natl Acad Sci U S A. 1981 Jan;78(1):13-5. doi: 10.1073/pnas.78.1.13.
4
[On the preparation of intermediates in cobyrinic acid biosynthesis by suspensions of Propionibacterium shermanii (author's transl)].关于谢氏丙酸杆菌悬浮液在钴胺酸生物合成中制备中间体的研究（作者译）
Hoppe Seylers Z Physiol Chem. 1977 Oct;358(10):1315-23.
5
Biosynthesis of porphyrins and related macrocycles. Part 10. Vitamin B12: biochemical derivation of cobyrinic acid from uroporphyrinogen III. Studies with corresponding ring c methyl heptacarboxylic prophyrinogen, and proof of seven intact methyl transfers.
J Chem Soc Perkin 1. 1977;2:166-78. doi: 10.1039/p19770000166.
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