维生素B12的生物合成：因子III掺入钴胺酸的方式。
Biosynthesis of vitamin B12: mode of incorporation of factor III into cobyrinic acid.
作者信息
Nussbaumer C, Imfeld M, Wörner G, Müller G, Arigoni D
出版信息
Proc Natl Acad Sci U S A. 1981 Jan;78(1):9-10. doi: 10.1073/pnas.78.1.9.
Abstract
Extensive chemical degradation of cobyrinic acid biosynthesized from a sample of factor III radiochemically labeled in its three methyl groups demonstrates that label is retained exclusively in the two methyl groups at positions C-2 and C-7 and confirms that the C-20 methyl group of the precursor is lost during formation of the corrin ring system.
摘要
对由在其三个甲基中进行放射化学标记的因子III样品生物合成的钴胺酸进行的广泛化学降解表明，标记仅保留在C-2和C-7位的两个甲基中，并证实前体的C-20甲基在卟啉环系统形成过程中丢失。
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本文引用的文献
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[On the preparation of intermediates in cobyrinic acid biosynthesis by suspensions of Propionibacterium shermanii (author's transl)].关于谢氏丙酸杆菌悬浮液在钴胺酸生物合成中制备中间体的研究（作者译）
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2
[On cobyrinic acid biosynthesis. Novel methylated hydroporphyrins and their role in cobyrinis acid formation (author's transl)].
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