维生素B12的生物合成：因子IV，厌氧途径中的一种新中间体。
Biosynthesis of vitamin B12: factor IV, a new intermediate in the anaerobic pathway.
作者信息
Scott A I, Stolowich N J, Wang J, Gawatz O, Fridrich E, Müller G
机构信息
Department of Chemistry, Texas A&M University, College Station 77843-3255, USA.
出版信息
Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14316-9. doi: 10.1073/pnas.93.25.14316.
Abstract
The structure of a novel tetradehydrocorrin, factor IV, isolated from Propionibacterium shermanii has been established by multidimensional NMR spectroscopy. Incorporation of radiolabeled factor IV into cobyrinic acid established the biointermediacy of this cobalt complex, whose structure has implications for the mechanisms of the anaerobic pathway to B12.
摘要
从谢氏丙酸杆菌中分离出的一种新型四脱氢钴胺素（因子IV）的结构已通过多维核磁共振光谱确定。将放射性标记的因子IV掺入钴胺酸中证实了这种钴配合物的生物中间产物性质，其结构对维生素B12厌氧合成途径的机制具有重要意义。
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本文引用的文献
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