Berthold F, von Hattingberg H M, Lampert F
Klin Padiatr. 1981 Mar;193(2):114-6. doi: 10.1055/s-2008-1034443.
During induction therapy of acute lymphoblastic leukemia a 10 year old boy developed a hyperuremic nephropathy and subsequently a staphylococcal septicemia at the beginning of the 3. week. Specific treatment was started leading to severe hypomagnesemia and generalized seizures with coma for 30 hours, which finally responded to magnesium replacement. The possible additive effect of nephropathy, gentamicin, and furosemide due to urinary loss of magnesium is discussed and should encourage further observations.
在急性淋巴细胞白血病诱导治疗期间，一名10岁男孩在第3周初出现了高尿素血症性肾病，随后发生了葡萄球菌败血症。开始进行特异性治疗，导致严重低镁血症和全身性惊厥伴昏迷30小时，最终对补充镁有反应。讨论了肾病、庆大霉素和呋塞米因镁经尿液丢失而可能产生的累加效应，这应促使进一步观察。
