MacDonald N, Steinhoff M C, Powell K R
Am J Dis Child. 1981 Jun;135(6):553-6. doi: 10.1001/archpedi.1981.02130300053018.
Only 13 cases of coccidioidomycosis in immunocompromised children have been previously reported. Of the reported cases, seven children had extrapulmonary involvement and died, while the six children with disease limited to the lungs survived the infection. A leukemic child who was treated for disseminated coccidioidomycosis and survived is described. Reviews of immunocompromised adult patients with coccidioidomycosis suggest factors that might be related to dissemination. Similar factors for immunocompromised children could not be defined, thus suggesting the need for more information regarding coccidioidomycosis.
此前仅报告过13例免疫功能低下儿童的球孢子菌病病例。在这些报告的病例中,7名儿童有肺外受累并死亡,而6名疾病局限于肺部的儿童感染后存活。本文描述了一名接受播散性球孢子菌病治疗并存活的白血病儿童。对免疫功能低下的成年球孢子菌病患者的回顾提示了可能与播散有关的因素。免疫功能低下儿童的类似因素尚无法确定,因此表明需要更多关于球孢子菌病的信息。