Hill C H
Ann N Y Acad Sci. 1980;355:262-6. doi: 10.1111/j.1749-6632.1980.tb21344.x.
Ascorbic acid has been found to interact with several elements in such a manner as to render them less available for animals. This property of the vitamin has a negative effect on the animals fed a copper-deficient diet, but a positive effect on those fed toxic levels of copper, selenium, vanadium, and cobalt. The effect of ascorbic acid in alleviating cadmium toxicity has been attributed to the effect of the vitamin on iron metabolism, since ferrous iron will also alleviate cadmium toxicity in the Japanese quail. The results of studies reported here indicate that iron will alleviate lead toxicity but ascorbic acid is ineffective. Ascorbic acid will alleviate mercury toxicity, but iron exacerbates this condition. For these two elements, the effects of iron and ascorbic acid are independent of each other.
已发现抗坏血酸与多种元素相互作用，其方式会使这些元素对动物的可用性降低。这种维生素特性对喂食缺铜饮食的动物有负面影响，但对喂食有毒水平铜、硒、钒和钴的动物有正面影响。抗坏血酸缓解镉毒性的作用归因于该维生素对铁代谢的影响，因为亚铁也能缓解日本鹌鹑的镉毒性。此处报告的研究结果表明，铁能缓解铅毒性，但抗坏血酸无效。抗坏血酸能缓解汞毒性，但铁会加剧这种情况。对于这两种元素，铁和抗坏血酸的作用相互独立。
