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人类的合成基因频率图谱与气候的选择效应

Synthetic gene frequency maps of man and selective effects of climate.

作者信息

Piazza A, Menozzi P, Cavalli-Sforza L L

出版信息

Proc Natl Acad Sci U S A. 1981 Apr;78(4):2638-42. doi: 10.1073/pnas.78.4.2638.

Abstract

The world distribution of 39 independent gene frequencies in human populations is analyzed by multivariate techniques and synthetic geographic maps. Most genetic variation is associated with longitude, with South Asia showing a tendency to be central. Also latitude and, more particularly, distance from the equator play a significant role in a way that suggests that climatic factors exercise selective pressures, especially for certain genes.

摘要

通过多变量技术和综合地理地图分析了人类群体中39个独立基因频率的全球分布情况。大多数遗传变异与经度相关,南亚呈现出处于中心位置的趋势。纬度,尤其是与赤道的距离也发挥着重要作用,这表明气候因素施加了选择压力,特别是对某些基因而言。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a6b/319405/9b73aa8cea50/pnas00655-0682-a.jpg

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