HLA - DW3与乳糜泻相关。
HLA-DW3 associated with coeliac disease.
作者信息
Keuning J J, Peña A S, van Leeuwen A, van Hooff J P, va Rood J J
出版信息
Lancet. 1976 Mar 6;1(7958):506-8. doi: 10.1016/s0140-6736(76)90294-4.
PMID:55781
Abstract
28 patients with coeliac disease (C.D.) were typed for the HLA-A, -B, and -D loci by several techniques. It was found that C.D. is primarily associated with the DW3 determinant and only secondarily with HLA-B8. The previously described association with HLA-B8 is explained by linkage disequilibrium between HLA-B8 and DW3.
摘要
采用多种技术对28例乳糜泻（C.D.）患者进行了HLA - A、- B和 - D位点分型。发现乳糜泻主要与DW3决定簇相关，其次才与HLA - B8相关。先前描述的与HLA - B8的关联是由HLA - B8与DW3之间的连锁不平衡所解释的。
Zotero 插件