Liebermann-Meffert D, Müller C, Allgöwer M
Scand J Gastroenterol Suppl. 1981;67:5-7.
Impaired gastric emptying in gastric ulcer patients has been explained by gastric hypomotility. Amplitude and duration of the contraction and integrated motor response to an electrical vagal stimulus, however, have been found to be significantly greater in 21 GU patients than in 25 DU and 6 combined ulcer patients. This shows hypermotility of the gastric muscle in GU patients. Delayed gastric emptying in GU disease, therefore, seems to result rather from antropyloric motor dysfunction than from gastric hypotony. Abnormal motility associated with duodeno-gastric reflux appears to be a key feature in the pathogenesis of gastric ulcer.
胃溃疡患者胃排空受损已被解释为胃动力不足。然而，已发现21例胃溃疡患者对电迷走神经刺激的收缩幅度、持续时间及综合运动反应明显大于25例十二指肠溃疡患者和6例复合性溃疡患者。这表明胃溃疡患者胃肌存在运动亢进。因此，胃溃疡疾病中胃排空延迟似乎更多是由胃幽门运动功能障碍引起，而非胃张力减退。与十二指肠-胃反流相关的异常运动似乎是胃溃疡发病机制的关键特征。
