Sierralta W, Pino A M, Magofke A M, Soto E, Devoto L
Arch Gynecol. 1981;230(3):189-94. doi: 10.1007/BF02111802.
Simultaneous determinations of 17 beta-estradiol dehydrogenase activity (17 beta-HSDH) and of estradiol (E2), estrone (E1), and progesterone (P) were made in homogenates of human tubal tissue. The oviducts were obtained from 16 multi-parous normal women who requested sterilization; surgery was performed at different phases of the menstrual cycle. A significant decrease of E2 concentration with a concomitant increase of E1 was observed in the secretory phase of the cycle. The activity of 17 beta-HSDH was highest in the early secretory phase of the cycle with a significant difference (p less than 0.05) from the proliferative phase values. The results support the concept, that the activity of 17 beta-HSDH in the oviduct is regulated by progesterone.
对人输卵管组织匀浆同时进行了17β - 雌二醇脱氢酶活性（17β - HSDH）以及雌二醇（E2）、雌酮（E1）和孕酮（P）的测定。输卵管取自16名要求绝育的经产妇；手术在月经周期的不同阶段进行。在月经周期的分泌期观察到E2浓度显著下降，同时E1增加。17β - HSDH的活性在月经周期的分泌早期最高，与增殖期的值有显著差异（p < 0.05）。结果支持这样一种观点，即输卵管中17β - HSDH的活性受孕酮调节。
