Block R M, Lewis R D, Sheats J B, Burke S H
Oral Surg Oral Med Oral Pathol. 1981 Jun;51(6):637-42. doi: 10.1016/s0030-4220(81)80015-1.
Pulp tissue from three experimental dogs was tested for its antigenicity before and after incubation with CMCP. Reaction to Arthus skin tests showed an increased response to pulp that had been incubated in CMCP, washed, then injected, as compared with pulp or CMCP alone. Hemagglutinating antibody titers (1:360 to 1:450 dilutions) were obtained from pulp tissue altered by CMCP. Inhibition tests showed the specificity of the antibody to be at a dilution titer of 1:350. Therefore, CMCP altered dog pulp tissue and rendered it antigenically active, and a specific humoral response was produced.
对三只实验犬的牙髓组织在与CMCP孵育前后进行抗原性测试。与单独的牙髓或CMCP相比,对阿尔图斯皮肤试验的反应显示,在CMCP中孵育、洗涤后注射的牙髓反应增强。从经CMCP改变的牙髓组织中获得了血凝抗体滴度(1:360至1:450稀释度)。抑制试验表明抗体的特异性在1:350稀释滴度。因此,CMCP改变了犬牙髓组织并使其具有抗原活性,并产生了特异性体液反应。