Budman D R, Lackner H, Berczeller P, Silber R
Am J Clin Pathol. 1981 Jun;75(6):840-3. doi: 10.1093/ajcp/75.6.840.
Thrombocytosis may reflect a primary myeloproliferative disorder or be a secondary reaction to other pathologic processes. Patients with persistent unexplained thrombocytosis meeting criteria of primary thrombocythemia had elevated levels of serum lactic dehydrogenase, whereas comparable patients with secondary thrombocytosis did not. The findings of an elevated serum lactic dehydrogenase supports the diagnosis of a myeloproliferative syndrome in patients who have unexplained thrombocytosis, and should be useful in the differential diagnosis of this hematologic abnormality.
血小板增多症可能反映原发性骨髓增殖性疾病，也可能是对其他病理过程的继发性反应。符合原发性血小板增多症标准的持续性不明原因血小板增多症患者血清乳酸脱氢酶水平升高，而继发性血小板增多症的类似患者则没有。血清乳酸脱氢酶升高的结果支持对不明原因血小板增多症患者骨髓增殖综合征的诊断，并且在这种血液学异常的鉴别诊断中应会有所帮助。
