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用于过敏皮肤试验的提取物效价的变化。

Variation in potency of extracts used for allergy skin tests.

作者信息

Hillas J L, Wilson J D

出版信息

N Z Med J. 1981 Jul 8;93(687):2-4.

PMID:6943460
Abstract

Extracts of 11 common inhalant allergens, produced by three different commercial suppliers, were compared by the skin prick test (SPT) in 21 atopic subjects. Good correlation was found between the three brands for positive reactions to grass pollens and English plantain pollen. Eighteen subjects with clinical sensitivity to house dust had diagnostically positive reactions to two of the house dust mite extracts, the third preparation produced no reactions that would be considered as diagnostically significant by the usual criteria. The extracts of house dust mixtures possessed little biological activity and were considered unsatisfactory for accurate diagnostic purposes. One of the three extracts of dog hair and dander produced false positive results in 17 of 21 subjects. The variability of reactions to fungi and animal hair and dander is discussed.

摘要

在21名特应性受试者中,通过皮肤点刺试验(SPT)比较了由三家不同商业供应商生产的11种常见吸入性变应原提取物。对于草花粉和大车前草花粉的阳性反应,发现这三个品牌之间具有良好的相关性。18名对屋尘临床敏感的受试者对两种屋尘螨提取物有诊断性阳性反应,按照通常标准,第三种制剂未产生可被视为具有诊断意义的反应。屋尘混合物提取物的生物活性很低,被认为不适合用于准确的诊断目的。狗毛和皮屑的三种提取物之一在21名受试者中的17名中产生了假阳性结果。文中讨论了对真菌以及动物毛发和皮屑反应的变异性。

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