Meyer-Schwickerath G, Fried M
Trans Ophthalmol Soc U K (1962). 1980 Apr;100(Pt 1):56-65.
Prophylactic treatment of retinal tears, holes, and degenerations has proved very effective in a convincing series of results. Ever since prophylactic treatment became available the number of patients treated prophylactically has been growing worldwide annually. While it will never be possible to prevent all retinal detachments, no significant fall in the rate of retinal detachment has been reported. Yet this is what we expect from prophylaxis. Most patients with manifest retinal detachment have not in fact received previous prophylactic treatment for various reasons. The ophthalmologist involved in prophylaxis is confronted with large numbers of patients. Preventive treatment has to be highly selective to be practicable and safe. Only lesions presenting a definite risk of retinal detachment should be treated. The criteria for treatment must be revised from time to time. Three types of failure should be noted: (a) Retinal detachment "because of" prophylaxis, (b) Retinal detachment "in spite of" prophylaxis, (c) Retinal detachment in cases in which prophylaxis was omitted because of a "false negative diagnosis". On the other hand overtreatment and misuse, i.e. prophylactic treatment of innocuous lesions, based on "false-positive diagnosis", apparently takes place without reducing the incidence of retinal detachment but resulting in expense and stress to the patient and in some cases even in complications of treatment. It seems unlikely that we have reached the final stage in the prevention of retinal detachment. Screening techniques, selection criteria, treatment, and follow-up should be improved. Until there are fewer detachments to operate upon, much remains to be done.
视网膜裂孔、孔洞及变性的预防性治疗已在一系列令人信服的结果中证明非常有效。自从有了预防性治疗方法以来,全球每年接受预防性治疗的患者数量一直在增加。虽然永远不可能预防所有视网膜脱离,但尚未有报告称视网膜脱离的发生率显著下降。然而,这正是我们对预防的期望。事实上,大多数明显视网膜脱离的患者由于各种原因此前并未接受预防性治疗。参与预防工作的眼科医生面对大量患者。预防性治疗必须高度有选择性,才切实可行且安全。只有那些有明确视网膜脱离风险的病变才应接受治疗。治疗标准必须不时修订。应注意三种失败情况:(a) “因”预防性治疗导致的视网膜脱离,(b) “尽管”进行了预防性治疗仍发生的视网膜脱离,(c) 因“假阴性诊断”而未进行预防性治疗的病例中发生的视网膜脱离。另一方面,基于“假阳性诊断”对无害病变进行过度治疗和滥用预防性治疗,显然在不降低视网膜脱离发生率的情况下发生,却给患者带来费用和压力,在某些情况下甚至导致治疗并发症。我们似乎尚未达到预防视网膜脱离的最后阶段。筛查技术、选择标准、治疗及随访都应改进。在需要手术治疗的视网膜脱离病例减少之前,仍有许多工作要做。