Monin C, Van Effenterre G, Andre-Sereys P, Haut J
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris.
J Fr Ophtalmol. 1994;17(3):167-74.
Prophylactic treatment in patients presenting Wagner-Stickler disease has not been yet well defined. We retrospectively studied twenty-two patients who had a retinal detachment on the first eye. Among the ten patients treated by peripheral confluent laser photocoagulation, five had a retinal detachment after a mean follow-up of fifteen months; with a 42% rate of spontaneous retinal detachment bilateralization, we can conclude that laser therapy has not been efficient. Four patients treated by focal or circular laser photocoagulation, cryotherapy or vitrectomy developed retinal detachment. Eight eyes treated by a preventive encircling scleral buckle did not develop retinal detachment, with a mean follow-up of twenty-one months. This follow-up is still too short, but greater than the mean bilateralization delay. Per and postoperative complications had no consequences.
对于患有瓦格纳-施蒂克勒病的患者，预防性治疗尚未明确界定。我们回顾性研究了22例第一眼发生视网膜脱离的患者。在接受周边融合激光光凝治疗的10例患者中，平均随访15个月后有5例发生视网膜脱离；由于视网膜脱离自发双侧化率为42%，我们可以得出结论，激光治疗效果不佳。接受局部或环形激光光凝、冷冻疗法或玻璃体切除术治疗的4例患者发生了视网膜脱离。接受预防性环扎巩膜扣带术治疗的8只眼未发生视网膜脱离，平均随访21个月。虽然该随访时间仍较短，但超过了平均双侧化延迟时间。围手术期并发症未产生不良后果。
