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测定红细胞质量在真性红细胞增多症诊断中的解读

Interpretation of measured red cell mass in the diagnosis of polycythaemia.

作者信息

Pearson T C, Glass U H, Wetherley-Mein G

出版信息

Scand J Haematol. 1978 Aug;21(2):153-62. doi: 10.1111/j.1600-0609.1978.tb02506.x.

DOI:10.1111/j.1600-0609.1978.tb02506.x
PMID:694427
Abstract

Expression of predicted and measured red cell mass (RCM) in terms of ml/kg body wt. lacks precision. The use of formulae for prediction of normal mean red cell mass derived from the blood volume prediction (BV) of Nadler et al (1962) has been examined. It is proposed that a more accurate determination of mean normal predicted red cell mass (MNRCM) is obtained by using: 0.47 X 0.91 X BV = MNRCM for males; 0.43 X 0.91 X BV = MNRCM for females. The MNRCMs given by these formulae agree with those given by predictions based on lean body mass and surface area. Examination of the '95% confidence limits' of the 'Nadler' prediction indicates that males with measured RCMs greater than 25% and females with measured RCMs greater than 30% above their MNRCM may be regarded as having polycythaemia.

摘要

以毫升/千克体重表示的预测和测量的红细胞量(RCM)缺乏精确性。对使用由纳德勒等人(1962年)的血容量预测(BV)得出的正常平均红细胞量预测公式进行了研究。有人提出,通过使用以下公式可以更准确地确定平均正常预测红细胞量(MNRCM):男性为0.47×0.91×BV = MNRCM;女性为0.43×0.91×BV = MNRCM。这些公式给出的MNRCM与基于瘦体重和表面积的预测结果一致。对“纳德勒”预测的“95%置信限”进行检查表明,测量的RCM比其MNRCM高25%以上的男性和高30%以上的女性可被视为患有红细胞增多症。

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Interpretation of measured red cell mass in the diagnosis of polycythaemia.测定红细胞质量在真性红细胞增多症诊断中的解读
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An improved method for the diagnosis of polycythaemia.一种用于诊断红细胞增多症的改良方法。
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