Shea J J, Emmett J R
J Laryngol Otol Suppl. 1981(4):130-8.
Currently there are three methods of treating patients with intractable tinnitus, a physical one using masking (Vernon, 1977), a psychosomatic method using biofeedback (House et al., 1977), and a chemical treatment using intravenous lidocaine and the oral anticonvulsants--carbamazepine, primidone and lidocaine amine. The latter seems to be the most promising, being easier to use, less time-consuming, more accurate to assess, and relying less on the patient's active participation and intelligence. The only disadvantages of the chemical method are the serious side-effects of the drugs in use. This can be managed by careful administration of these drugs and monitoring of the patient. In the future, new anticonvulsants with fewer side-effects will certainly be produced. It may be that chemical treatment can be combined with the masking and/or the biofeedback methods with a synergistic result. Another possible use of carbamazepine is in the treatment of palatal myoclonus and other similar disorders. Further clinical studies are needed to corroborate this application of the treatment.
目前有三种治疗顽固性耳鸣患者的方法,一种是使用掩蔽疗法的物理方法(弗农,1977年),一种是使用生物反馈的身心疗法(豪斯等人,1977年),还有一种是使用静脉注射利多卡因和口服抗惊厥药——卡马西平、扑米酮和利多卡因胺的化学疗法。后一种方法似乎最有前景,因为它使用起来更简便、耗时更少、评估更准确,而且对患者的主动参与和智力依赖较小。化学方法唯一的缺点是所用药物的严重副作用。这可以通过谨慎给药和对患者进行监测来处理。未来肯定会生产出副作用更少的新型抗惊厥药。化学疗法有可能与掩蔽疗法和/或生物反馈方法相结合,产生协同效果。卡马西平的另一个可能用途是治疗腭肌阵挛和其他类似疾病。需要进一步的临床研究来证实这种治疗方法的应用。