Wilke W S, Sheeler L R, Makarowski W S
J Rheumatol. 1981 Jul-Aug;8(4):626-31.
Eight patients who initially presented with signs and symptoms of the fibrositis syndrome, without overt hypothyroid disease, were found to have chemical evidence of hypothyroidism. Myalgic symptoms resolved in 6 of 8 patients treated with low dose thyroid replacement. In addition, another hypothesis of pathophysiology of the myalgic symptoms observed in patients with hypothyroidism related to sleep disturbance is offered.
8名最初表现为纤维炎综合征体征和症状、无明显甲状腺功能减退疾病的患者，经化学检查发现存在甲状腺功能减退。8名接受低剂量甲状腺替代治疗的患者中，有6名的肌痛症状得到缓解。此外，还提出了另一种关于甲状腺功能减退患者中观察到的与睡眠障碍相关的肌痛症状病理生理学的假说。
