Anderson M W, Izutsu K T, Rice J C
Oral Surg Oral Med Oral Pathol. 1981 Nov;52(5):495-500. doi: 10.1016/0030-4220(81)90361-3.
Electrolyte and protein concentrations were measured in parotid saliva samples obtained from patients receiving localized, fractionated, neutron and gamma irradiation for the treatment of cancer. Salivary sodium chloride concentration increased transiently but then usually decreased to preirradiation values after 2 weeks of therapy. There were concurrent decreases in salivary flow rate, pH, and bicarbonate concentration. The decreases in sodium chloride concentration and flow rate are inconsistent with a previously suggested, irradiation-induced ductal sodium resorption defect. The findings contribute toward understanding how salivary gland physiology is altered in irradiation injury.
对接受局部、分次中子和伽马射线照射以治疗癌症的患者所采集的腮腺唾液样本中的电解质和蛋白质浓度进行了测量。唾液中氯化钠浓度短暂升高，但在治疗2周后通常会降至照射前水平。同时，唾液流速、pH值和碳酸氢盐浓度均下降。氯化钠浓度和流速的下降与先前提出的照射诱导的导管钠重吸收缺陷不一致。这些发现有助于理解唾液腺生理在辐射损伤中是如何改变的。
